In 2016,Abbasi, M. A.; Tariq, S.; Aziz-ur-Rehman; Siddiqui, S. Z.; Ahmad, I.; Malik, R.; Shah, S. A. A. published 《Synthesis of some new N-substituted-N-(2,3-dihydro-[1,4]benzodioxin-6-yl)-4-acetamidobenzenesulfonamides as valuable antibacterial agents》.Russian Journal of Bioorganic Chemistry published the findings.Name: 1,2-Diiodoethane The information in the text is summarized as follows:
The aim of the present research was to investigate the antibacterial potential of some N-substituted sulfonamides bearing a benzodioxane moiety, I (R = Et, iso-Pr, CH2Ph, 2-ClC6H4CH2, etc.). The synthesis was started by reacting N-2,3-dihydrobenzo[1,4]dioxin-6-amine with 4-acetamidobenzene-1-sulfonyl chloride in the presence of 10% aqueous Na2CO3 solution to yield N-(2,3-dihydrobenzo[1,4]-dioxin-6-yl)-4-acetamidobenzenesulfonamide (II). II was further reacted with alkyl/aralkyl halides in DMF and lithium hydride as a base to obtain products I. All the synthesized compounds were characterized by spectral data (IR, 1H NMR, EI-MS, and HR-MS). The compounds were tested for antibacterial activity and most of them exhibited potent therapeutic potential against various Gram-neg. and Gram-pos. strains. The results came from multiple reactions, including the reaction of 1,2-Diiodoethane(cas: 624-73-7Name: 1,2-Diiodoethane)
1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the SimmonsSmith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Name: 1,2-Diiodoethane
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com