《Electrophilic Vinylation of Thiols under Mild and Transition Metal-Free Conditions》 was published in Angewandte Chemie, International Edition in 2020. These research results belong to Castoldi, Laura; Di Tommaso, Ester Maria; Reitti, Marcus; Graefen, Barbara; Olofsson, Berit. Name: 2-Iodobenzoic acid The article mentions the following:
The iodine(III) reagents vinylbenziodoxolones (VBX) were employed to vinylate a series of aliphatic and aromatic thiols, providing E-alkenyl sulfides with complete chemo- and regioselectivity, as well as excellent stereoselectivity [e.g., PhSH + VBX I → II (87%, >20:1 E/Z) + PhSSPh (7%) in THF solvent using tBuOK as base]. The methodol. displays high functional group tolerance and proceeds under mild and transition metal-free conditions without the need for excess substrate or reagents. Mercaptothiazoles could be vinylated under modified conditions, resulting in opposite stereoselectivity compared to previous reactions with vinyliodonium salts. Novel VBX reagents with substituted benziodoxolone cores were prepared, and improved reactivity was discovered with a dimethyl-substituted core. In the experimental materials used by the author, we found 2-Iodobenzoic acid(cas: 88-67-5Name: 2-Iodobenzoic acid)
2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Name: 2-Iodobenzoic acid
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com