《Polarity-Reversal Strategy for the Functionalization of Electrophilic Strained Molecules via Light-Driven Cobalt Catalysis》 was published in Journal of the American Chemical Society in 2020. These research results belong to Ociepa, Michal; Wierzba, Aleksandra J.; Turkowska, Joanna; Gryko, Dorota. Safety of 1-Iodo-4-methylbenzene The article mentions the following:
Strain-release-driven methodol. is a powerful tool for accessing structural motifs, highly desirable by the pharmaceutical industry. The reactivity of spring-loaded cyclic reagents is dominated by transformations relying on their inherent electrophilic reactivity. Herein, we present a polarity-reversal strategy based on light-driven cobalt catalysis, which enables the generation of nucleophilic radicals through strain release. The applicability of this methodol. is demonstrated by the design of two distinct types of reactions: Giese-type addition and Co/Ni-catalyzed cross-coupling. Moreover, a series of electrochem., spectroscopic, and kinetic experiments as well as X-ray structural anal. of the intermediate alkylcobalt(III) complex give deeper insight into the mechanism of the reaction. In the experiment, the researchers used 1-Iodo-4-methylbenzene(cas: 624-31-7Safety of 1-Iodo-4-methylbenzene)
1-Iodo-4-methylbenzene(cas: 624-31-7) undergoes Suzuki-Miyaura coupling reaction with phenylboronic acid catalyzed by (Ni,Mg)3Si2O5(OH)4 solid-solution nanotubes loaded with palladium.Safety of 1-Iodo-4-methylbenzene
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com