In 2022,Thakare, Milind S.; Pawar, Nilesh S.; Adole, Vishnu A.; Patil, Dipak B.; Patil, Vikas published an article in Journal of the Indian Chemical Society. The title of the article was 《Reactive sensing of gold (III) by coumarin tethered fluorescent probe through alkyne activation》.Product Details of 88-67-5 The author mentioned the following in the article:
A novel strategy, involving anchoring and un-anchoring of coumarin based fluorophore, has been established for the selective detection of Au3+ species. Selective sensing of Gold (Au3+) was triggered due to alkynophilicity of gold ions to create lateral fluorescence of a latent fluorophore. The 4-methyl-2-oxo-2H-chromen-7-yl 2-(2-phenylethynyl) benzoate (CEB) probe was synthesized by reacting 7-hydroxy-4-methylcoumarin with iodo-benzoic acid. CEB probe has an absorption at 300 nm and 335 nm which decreases gradually and new absorption appeared at 406 nm due to Au3+ promoted ester hydrolysis selectively over other metal ions with great sensitivity, which accompanies a turn on fluorescence change produced by 7-hydroxy coumarin. The principle behind this sensing strategy is activation of triple bond induced uniquely by Au+3 ions leading to cascade and delivers active fluorophore. The sensing mechanism was proposed and supported by 1H NMR, MS and TD-DFT experiments The d. functional theory (DFT) and time dependent d. functional theory (TD-DFT) theor. results of the CEB-probe and Au3+ reaction is in good agreement with the exptl. results. Addnl., probe could be well incorporated onto the test strips for effective detection of Au3+.2-Iodobenzoic acid(cas: 88-67-5Product Details of 88-67-5) was used in this study.
2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine.Product Details of 88-67-5 In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com