The author of 《[3+3] Annulation via Ring Opening/Cyclization of Donor-Acceptor Cyclopropanes with (Un)symmetrical Ureas: A Quick Access to Highly Functionalized Tetrahydropyrimidinones》 were Taily, Irshad Maajid; Saha, Debarshi; Banerjee, Prabal. And the article was published in European Journal of Organic Chemistry in 2019. Category: iodides-buliding-blocks The author mentioned the following in the article:
A mild and straight-forward access to pharmacol. privileged tetrahydropyrimidinones exploiting readily available Donor-Acceptor cyclopropanes (DACs) is reported. This methodol. involves the Lewis acid catalyzed synthesis of ureido-malonates from (un)sym. ureas and DACs followed by I2-base mediated cyclization to their corresponding tetrahydropyrimidinones [e.g., I + II → III → IV]. The cyclization protocol involves nucleophilic attack of the nitrogen of urea on the newly generated electrophilic acceptor end of DAC. The post functionalization offered potential biol. active mols. After reading the article, we found that the author used Trimethylsulfoxonium iodide(cas: 1774-47-6Category: iodides-buliding-blocks)
Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.Category: iodides-buliding-blocks
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com