Recommanded Product: (R)-3,3′-Diiodo-2,2′-bis(methoxymethoxy)-1,1′-binaphthaleneOn May 7, 1997 ,《Development of highly enantioselective polymeric catalysts using rigid and sterically regular chiral polybinaphthols》 appeared in Journal of the American Chemical Society. The author of the article were Huang, Wei-Sheng; Hu, Qiao-Sheng; Zheng, Xiao-Fan; Anderson, Julie; Pu, Lin. The article conveys some information:
A highly enantioselective polymeric catalyst based on sterically regular and rigid chiral polymers has been developed by systematically modifying the microenvironment of the catalytic centers in these polymers. These polymers are constructed by incorporating optically active 1,1′-bi-2-naphthol units into a rigid polymer chain, and are expected to have well-defined microenvironments around their catalytic sites when used in catalysis. The asym. reaction of aldehydes with diethylzinc catalyzed by the polybinaphthols to generate chiral alcs. has been studied. It was discovered that the polymer prepared by Suzuki coupling of the methoxymethyl group protected (R)-3,3′-diiodo-1,1′-bi-2-naphthol with 2,5-bis(hexyloxy)-1,4-phenylenediboronic acid, followed by hydrolysis, can produce chiral alcs. in up to 94% ee for the asym. reaction. It was also found that the high enantioselectivity is reproducible even when polymers prepared by different methods and with different mol. weights are used. The chiral polymer can be easily separated from the reaction mixture by simple precipitation and the recycled polymer shows the same enantioselectivity as the original polymer. This study provides a new direction to the design and synthesis of enantioselective polymeric catalysts. In the experiment, the researchers used (R)-3,3′-Diiodo-2,2′-bis(methoxymethoxy)-1,1′-binaphthalene(cas: 189518-78-3Recommanded Product: (R)-3,3′-Diiodo-2,2′-bis(methoxymethoxy)-1,1′-binaphthalene)
(R)-3,3′-Diiodo-2,2′-bis(methoxymethoxy)-1,1′-binaphthalene(cas: 189518-78-3) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Recommanded Product: (R)-3,3′-Diiodo-2,2′-bis(methoxymethoxy)-1,1′-binaphthalene
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com