Reference of 1-Bromo-3-iodobenzeneIn 2020 ,《Microwave irradiated palladium-catalyzed cascade type cross coupling of phenols and halides for the synthesis of polyphenolic ethers》 appeared in International Journal of Organic Chemistry. The author of the article were Al-Masum, Mohammad; Alalwan, Houra A.. The article conveys some information:
A mild, cascade type methodol. was developed for the synthesis of poly-phenolic ethers e.g., 1,3,5-tris[4-(trifluoromethoxy)phenoxy]benzene by the palladium-catalyzed cross coupling of phenols ROH (R = Ph, 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl, 4-(trifluoromethoxy)phenyl, 2-(trifluoromethoxy)phenyl) and halo compounds such as 1,3,5-tribromobenzene, 1,3-dibromopropane, 1-bromo-3-iodobromobenzene and bromo iodomethane under microwave heating. In most cases, reactions run in neat conditions and in some cases, IPA/water mixture, and 1,4-dioxane were employed as solvents to furnish the products. By applying this new method, it was able to synthesize and purify a good number of polyether compounds e.g. 1,3,5-tris[4-(trifluoromethoxy)phenoxy]benzene with complete spectral data. In addition to this study using 1-Bromo-3-iodobenzene, there are many other studies that have used 1-Bromo-3-iodobenzene(cas: 591-18-4Reference of 1-Bromo-3-iodobenzene) was used in this study.
1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Reference of 1-Bromo-3-iodobenzene
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com