《A convenient synthesis of N,N’-dibenzyl-2,4-diaminopyrimidine-2′-deoxyribonucleoside and 1-methyl-2′-deoxypseudoisocytidine》 was written by Wellington, Kevin W.; Ooi, Hua Chee; Benner, Steven A.. Name: 2-Amino-5-iodopyrimidin-4(1H)-one And the article was included in Nucleosides, Nucleotides & Nucleic Acids on April 30 ,2009. The article conveys some information:
The syntheses of N,N’-dibenzyl-2,4-diaminopyrimidine-2′-deoxyribonucleoside and 1-methyl-2′-deoxypseudoisocytidine via Heck coupling are described. A survey of the attempts to use the Heck coupling to synthesize N,N’-dibenzyl-2,4-diaminopyrimidine-2′-deoxyribonucleoside is provided, indicating a remarkable diversity in outcome depending on the specific heterocyclic partner used. In the experimental materials used by the author, we found 2-Amino-5-iodopyrimidin-4(1H)-one(cas: 3993-79-1Name: 2-Amino-5-iodopyrimidin-4(1H)-one)
2-Amino-5-iodopyrimidin-4(1H)-one(cas: 3993-79-1) belongs to anime. Primary amines having a tertiary alkyl group (R3CNH2) are difficult to prepare with most methods but are made industrially by the Ritter reaction. In this method a tertiary alcohol reacts with hydrogen cyanide (HCN) in the presence of a concentrated strong acid; a formamide, RNH―CHO, is formed first, which then undergoes hydrolysis.Name: 2-Amino-5-iodopyrimidin-4(1H)-one
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com