Zhao, Lulu; Dong, Yanan; Xia, Qiangqiang; Bai, Jianfei; Li, Yuehui published the artcile< Zn-Catalyzed Cyanation of Aryl Iodides>, Application In Synthesis of 2265-92-1, the main research area is aryl cyanide preparation; formamide aryl iodide cyanation zinc catalyst.
An efficient method for the synthesis of cyanides such as ArCN [Ar = 4-ClC6H4, 4-MeC6H4, 1-naphthyl, etc.] via zinc-catalyzed cyanation of aryl iodides with formamide as cyanogen source was reported. The transformation was promoted by bisphosphine Nixantphos ligand. Under optimized conditions, a variety of electron-donating and electron-withdrawing aryl iodides were converted into the nitrile products ArCN in good to excellent yields. This approach was an exceedingly simple and benign method for the synthesis of aryl nitriles ArCN and was likely to proceed via a dinuclear-Zn concerted catalysis.
Journal of Organic Chemistry published new progress about Aryl iodides Role: RCT (Reactant), RACT (Reactant or Reagent). 2265-92-1 belongs to class iodides-buliding-blocks, and the molecular formula is C6H3F2I, Application In Synthesis of 2265-92-1.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com