The author of 《Synthesis of indoles and quinazolines via additive-controlled selective C-H activation/annulation of N-arylamidines and sulfoxonium ylides》 were Lai, Ruizhi; Wu, Xiaohua; Lv, Songyang; Zhang, Chen; He, Maoyao; Chen, Yuncan; Wang, Qiantao; Hai, Li; Wu, Yong. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2019. Recommanded Product: Trimethylsulfoxonium iodide The author mentioned the following in the article:
Selective synthesis of indole I (R1 = 5-OCH3, 6-F, 4,6-(CH3)2, etc.; R2 = CH3, (CH2)2CH3, CH2CH(CH3)2, (CH2)2OCH3, CH2C6H5; R3 = C6H5, 2-naphthyl, 2H-1,3-benzodioxol-5-yl, etc.) and quinazoline products II (R4 = 6-OCH3, 5-Cl, 6-C(O)CH3)was achieved through a precise control of the C-H activation/annulation by changing the additives from NaOAc to CuF2/CsOAc. This strategy constructs indoles I and quinazoline scaffolds II efficiently, and hence it is greatly used in pharmaceutical, agricultural and chem. industries.Trimethylsulfoxonium iodide(cas: 1774-47-6Recommanded Product: Trimethylsulfoxonium iodide) was used in this study.
Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Recommanded Product: Trimethylsulfoxonium iodide
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com