Synthetic Route of C5H4INIn 2021 ,《Coupling of thiols and aromatic halides promoted by diboron derived super electron donors》 appeared in Chemical Communications (Cambridge, United Kingdom). The author of the article were Franco, Mario; Vargas, Emily L.; Tortosa, Mariola; Cid, M. Belen. The article conveys some information:
Authors have proven that pyridine-boryl complexes can be used as superelectron donors to promote the coupling of thiols and aromatic halides through a SRN1 mechanism. The reaction is efficient for a broad substrate scope, tolerating heterocycles including pyridines, enolizable or reducible functional groups. The method has been applied to intermediates in drug synthesis as well as interesting functionalized polythioethers through a controlled and consecutive intramol. electron transfer process. In the part of experimental materials, we found many familiar compounds, such as 4-Iodopyridine(cas: 15854-87-2Synthetic Route of C5H4IN)
4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.Synthetic Route of C5H4IN
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com