A new synthetic route of 180258-46-2

I hope my short article helps more people learn about this compound(Ethyl 4-amino-1-methyl-1H-imidazole-2-carboxylate hydrochloride)COA of Formula: C7H12ClN3O2. Apart from the compound(180258-46-2), you can read my other articles to know other related compounds.

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography, published in 2008-09-02, which mentions a compound: 180258-46-2, Name is Ethyl 4-amino-1-methyl-1H-imidazole-2-carboxylate hydrochloride, Molecular C7H12ClN3O2, COA of Formula: C7H12ClN3O2.

The biodistribution profiles in mice of two pyrrole-imidazole polyamides were determined by PET. Pyrrole-imidazole polyamides are a class of small mols. that can be programmed to bind a broad repertoire of DNA sequences, disrupt transcription factor-DNA interfaces, and modulate gene expression pathways in cell culture experiments The 18F-radiolabeled polyamides were prepared by oxime ligation between 4-[18F]-fluorobenzaldehyde and a hydroxylamine moiety at the polyamide C terminus. Small animal PET imaging of radiolabeled polyamides administered to mice revealed distinct differences in the biodistribution of a 5-ring β-linked polyamide vs. an 8-ring hairpin, which exhibited better overall bioavailability. In vivo imaging of pyrrole-imidazole polyamides by PET is a min. first step toward the translation of polyamide-based gene regulation from cell culture to small animal studies.

I hope my short article helps more people learn about this compound(Ethyl 4-amino-1-methyl-1H-imidazole-2-carboxylate hydrochloride)COA of Formula: C7H12ClN3O2. Apart from the compound(180258-46-2), you can read my other articles to know other related compounds.

Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com