Bel-Rhlid, Rachid; Talmon, Jean P.; Fay, Laurent B.; Juillerat, Marcel A. published the article 《Biodegradation of 3-Chloro-1,2-propanediol with Saccharomyces cerevisiae》. Keywords: chloropropanediol biodegradation Saccharomyces cerevisiae.They researched the compound: (2S)-(+)-3-Chloropropane-1,2-diol( cas:60827-45-4 ).Formula: C3H7ClO2. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:60827-45-4) here.
A novel enzymic dehalogenating activity of 3-chloro-1,2-propanediol (3-MCPD) with Saccharomyces cerevisiae (baker’s yeast) is reported. All bioconversion assays were carried out under aerobic conditions at 28°, and the kinetics were monitored. The biodegradation was performed at different pH values (6.2, 7.0, and 8.2), in the presence and absence of glucose, using racemic 3-MCPD at two different concentrations (7.3 μmol/L and 27 mmol/L). Optimal conversion (68%) of racemic (R,S)-3-MCPD at a concentration of 27 mmol/L was achieved after 48 h of reaction time, at pH 8.2, and in the presence of glucose. At a concentration of 7.3 μmol/L, 73% degradation was observed after 72 h, at pH 8.2 and in the absence of glucose. Under the same exptl. conditions, the conversion of pure (S)-3-MCPD (85%) was higher than that of the (R)-enantiomer (60%).
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