Something interesting about 4553-62-2

From this literature《Chemoenzymic Production of Lactams from Aliphatic α,ω-Dinitriles》,we know some information about this compound(4553-62-2)HPLC of Formula: 4553-62-2, but this is not all information, there are many literatures related to this compound(4553-62-2).

Gavagan, John E.; Fager, Susan K.; Fallon, Robert D.; Folsom, Patrick W.; Herkes, Frank E.; Eisenberg, Amy; Hann, Eugenia C.; DiCosimo, Robert published an article about the compound: 2-Methylglutaronitrile( cas:4553-62-2,SMILESS:N#CC(C)CCC#N ).HPLC of Formula: 4553-62-2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:4553-62-2) through the article.

Five- and six-membered ring lactams have been prepared by first converting an aliphatic α,ω-dinitrile to an ω-cyano carboxylic acid ammonium salt, using a microbial cell catalyst having an aliphatic nitrilase activity (Acidovorax facilis 72W, ATCC 55746) or a combination of nitrile hydratase and amidase activities (Comamonas testosteroni 5-MGAM-4D, ATCC 55744). The ω-cyano carboxylic acid ammonium salt was then directly converted to the lactam by hydrogenation in aqueous solution, without isolation of the intermediate ω-cyano carboxylic acid or ω-amino carboxylic acid. Only one of two possible lactam products was produced from α-alkyl-substituted α,ω-dinitriles, where the nitrilase of A. facilis 72W regioselectively hydrolyzed only the ω-cyano group to produce a single cyano carboxylic acid ammonium salt in greater than 98% yield.

From this literature《Chemoenzymic Production of Lactams from Aliphatic α,ω-Dinitriles》,we know some information about this compound(4553-62-2)HPLC of Formula: 4553-62-2, but this is not all information, there are many literatures related to this compound(4553-62-2).

Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com