Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 60827-45-4, is researched, SMILESS is OC[C@H](O)CCl, Molecular C3H7ClO2Journal, Tetrahedron: Asymmetry called Application of cyclic sulfates in the synthesis of enantiomers of 1-[3-(4-aryl-piperazin-1-yl)-2-hydroxy-propyl]-pyrrolidin-2-one, Author is Kulig, Katarzyna; Boba, Agnieszka; Bielejewska, Anna; Gorska, Magdalena; Malawska, Barbara, the main research direction is chlorodihydroxypropane thionyl chloride cyclic sulfate cyclization ring opening condensation; arylpiperazinyl hydroxypropylpyrrolidinone preparation.Related Products of 60827-45-4.
The synthesis of enantiomers of 1-[3-(4-aryl-piperazin-1-yl)-2-hydroxy-propyl]-pyrrolidin-2-one derivatives, i.e. I, is described. These enantiomers were synthesized starting from (R)- or (S)-1-chloro-2,3-dihydroxypropane using relevant cyclic sulfates as chiral intermediates. The enantiomeric purities of the final compounds were in the range of 99.3-100.0%, as determined by high performance liquid chromatog. The final compounds were found to display moderate potency as ligands for α1-adrenoreceptors.
There is still a lot of research devoted to this compound(SMILES：OC[C@H](O)CCl)Related Products of 60827-45-4, and with the development of science, more effects of this compound(60827-45-4) can be discovered.
Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com