In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Inhibition of fructolysis in boar spermatozoa by the male antifertility agent (S)-α-chlorohydrin, published in 1982, which mentions a compound: 60827-45-4, Name is (2S)-(+)-3-Chloropropane-1,2-diol, Molecular C3H7ClO2, Name: (2S)-(+)-3-Chloropropane-1,2-diol.
The male antifertility agent (S)-α-chlorohydrin [60827-45-4] strongly inhibited the oxidative metabolism of fructose [57-48-7] by boar spermatozoa in vitro. The result of this action, which has been deduced to be an inhibition of glyceraldehyde phosphate dehydrogenase, caused an accumulation of fructose 1,6-bisphosphate [488-69-7] and the triose phosphates, and a decrease in substrate-level phosphorylation with a concomitant lowering of the energy charge potential of the spermatozoa. (R)-α-chlorohydrin [57090-45-6] Had no inhibitory activity on fructolysis. A study of the comparative metabolism of (R)-[3-36Cl]-α-chlorohydrin and (R,S)-[3-36Cl]-α-chlorohydrin by boar spermatozoa showed that it is the (S)-isomer that specifically undergoes a process of oxidative metabolism to (R)-3-chlorolactaldehyde [84607-54-5]. This endogenous oxidation product, which has the same absolute configuration as the substrate for glyceraldehyde phosphate dehydrogenase, may be the active metabolite of (S)-α-chlorohydrin that inhibits this enzyme. Exogenous (R,S)-3-chlorolactaldehyde [84709-24-0] inhibited the oxidative metabolism of fructose by boar spermatozoa, apparently by a mechanism similar to that of (S)-α-chlorohydrin.
There is still a lot of research devoted to this compound(SMILES：OC[C@H](O)CCl)Name: (2S)-(+)-3-Chloropropane-1,2-diol, and with the development of science, more effects of this compound(60827-45-4) can be discovered.
Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com