Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 755027-18-0, name is 1-Bromo-4-iodo-2-methoxybenzene, This compound has unique chemical properties. The synthetic route is as follows., HPLC of Formula: C7H6BrIO
1-Bromo-4-iodo-2-methoxybenzene (50 g, 160 mmol) was suspended in CH2CI2 (75 mL) at -10 C. Boron tribromide (250 mL, 250 mmol, 1M in CH2CI2,) was cannulated in over 30 min, with the internal temperature remaining below 0 C throughout the addition. After the addition, the mixture was stirred at 0C for 1 hour, and then at room temperature for 16 hours. The mixture was cooled in an ice bath. 10% Aqueous Na2C03 (250 mL) was added in portions. The mixture was then partitioned between H20 and CH2Cl2. The CH2Cl2 layer was dried over MgS04 and then filtered. 2-Bromo-5-iodophenol (46 g, 96%) was obtained from the filtrate as a pinkish-white solid. 1H NMR (acetone-< d: 9.24 (br s, 1H), 7.38 (d, 7=2 Hz, 1H), 7.31 (d, 7=8.5 Hz, 1H), 7.17 (dd, 7=8.5 Hz, 2 Hz, 1H).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 755027-18-0.
Reference:
Patent; PTC THERAPEUTICS, INC.; CHEN, Guangming; BHATTACHARYYA, Anuradha; JIANG, Yao; KARP, Gary, Mitchell; NARASIMHAN, Jana; TURPOFF, Anthony; ZHANG, Nanjing; (0 pag.)WO2020/5882; (2020); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com