9/8/2021 News Extracurricular laboratory: Synthetic route of 63262-06-6

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,4-Dibromo-2,5-diiodobenzene, other downstream synthetic routes, hurry up and to see.

Electric Literature of 63262-06-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 63262-06-6, name is 1,4-Dibromo-2,5-diiodobenzene belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

To a stirred solution of 2-(tributylstannyl)thiophene (20.7 g, 55.3 mmol) and1,4-dibromo-2,5-diiodobenzene (13.5 g, 27.7 mmol) in dry DMF (100 mL) was addedPd(PPh3)2Cl2 (0.78 g, 1.12 mmol). The mixture was stirred for 40 h at 80 C. Aftercooling to room temperature, the reaction mixture was poured into water and thenextracted with toluene. The combined organic layers were washed with water and driedover anhydrous Na2SO4. After filtration and evaporation, the crude product wasrecrystallized from methanol to provide 8 as a white solid (yield = 10.3 g, 93%).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,4-Dibromo-2,5-diiodobenzene, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Komiyama, Hideaki; Adachi, Chihaya; Yasuda, Takuma; Beilstein Journal of Organic Chemistry; vol. 12; (2016); p. 1459 – 1466;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com