Adding a certain compound to certain chemical reactions, such as: 32024-15-0, name is 3-Iodo-4,5-dimethoxybenzaldehyde, belongs to iodides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 32024-15-0, COA of Formula: C9H9IO3
To a mixture of N-(tert-butyl)hydroxylamine hydrochloride (S3) (930 mg, 7.44 mmol), 3-iodo-4,5-dimethoxybenzaldehyde (S4) (3.27 g, 11.2 mmol, 1.50 equiv), triethylamine (2.06 mL, 14.9 mmol, 2.00 equiv), and MgSO4 (4.46 g, 37.2 mmol, 5.00 equiv) were added toluene (100 mL) at room temperature and the mixture was refluxed with stirring for 3 days. After cooling to room temperature, to the mixture was added water (50 mL) and the mixture was extracted with EtOAc (50 mL × 3). The combined organic extract was washed with aqueous saturated solution of sodium bicarbonate (20 mL), brine (20 mL), dried (Na2SO4),and after filtration, the filtrate was concentrated under reduced pressure. The residue was purified by flash column chromatography (silica-gel 70.0 g, n-hexane/EtOAc = 10/1) to give N-tert-butyl(3-iodo-4,5-dimethoxybenzylidene)amine N-oxide (9) (1.69 g, 4.66 mmol, 62.6%) as a colorless solid.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Iodo-4,5-dimethoxybenzaldehyde, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Yoshida, Suguru; Uchida, Keisuke; Hosoya, Takamitsu; Chemistry Letters; vol. 44; 5; (2015); p. 691 – 693;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com