Synthetic Route of 620-05-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 620-05-3, name is (Iodomethyl)benzene belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
General procedure for the synthesis of diorganyl selenides and sulfides: commercially available Zn dust (33 mg, 0.5 mmol) and PhSeSePh/PhSSPh (0.5 mmol) and 15 muL of HCl 1N were added to BMIM-BF4 (0.5 mL) at room temperature under nitrogen. The mixture was allowed to stir for 2-3 min. Then corresponding organic halides (1 mmol) was slowly added. The reaction mixture was allowed to stir until the color change (monitored by TLC and assisted by visual observation). The mixture was then extracted with ether (3×15 mL), and the combined ether extract was washed with brine, dried (MgSO4), and evaporated to leave the crude product. Purification by column chromatography over silica gel (hexane/ethyl acetate 98:2) furnished the corresponding products.
The synthetic route of (Iodomethyl)benzene has been constantly updated, and we look forward to future research findings.
Reference:
Article; Narayanaperumal, Senthil; Alberto, Eduardo E.; Gul, Kashif; Kawasoko, Cristiane Yuriko; Dornelles, Luciano; Rodrigues, Oscar E.D.; Braga, Antonio Luiz; Tetrahedron; vol. 67; 25; (2011); p. 4723 – 4730;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com