Application of 2043-57-4, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 2043-57-4 as follows.
General procedure: 2-(Perfluorodecyl)ethyl iodide (5.26 g, 7.81 mmol), 4-mercaptophenol (0.94 g, 7.44 mmol), andK2CO3 (2.06 g, 14.88 mmol) was added in acetone (80 mL) in a 200 mL recovery flask, and theresulting mixture was heated at reflux for 3 days. The reaction mixture was allowed to cool toroom temperature. After 1 N HCl aqueous solution was added to the mixture until pH ? 3,saturated NaCl aqueous solution (100 mL) was added to it and the resulting solution wasextracted with EtOAc (100 mL × 3). The organic layers were combined and dried with MgSO4,and after filtration, the filtrate was concentrated using a rotary evaporator under reduced pressure.The crude product was purified by silica gel column chromatography (eluent: CHCl3) to give A-10 (3.00 g, 4.46 mmol) in 60% yield as colorless powder.
According to the analysis of related databases, 2043-57-4, the application of this compound in the production field has become more and more popular.
Reference:
Article; Yoshida, Tomohiro; Hirakawa, Tomomi; Nakamura, Toru; Yamada, Yasuhiro; Tatsuno, Hiroko; Hirai, Masayuki; Morita, Yuki; Okamoto, Hiroaki; Bulletin of the Chemical Society of Japan; vol. 88; 10; (2015); p. 1447 – 1452;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com