The chemical industry reduces the impact on the environment during synthesis 3-Bromo-5-iodobenzoic acid. I believe this compound will play a more active role in future production and life.
Reference of 188815-32-9, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 188815-32-9, name is 3-Bromo-5-iodobenzoic acid, This compound has unique chemical properties. The synthetic route is as follows.
EXAMPLE 4.539; 3-(5 -Chloropyridin-2-ylV 5-f 1 -hydroxy- 1 -methylethylVN- U 1 R )- 1 – 1 -oxido-6- f trifluoromethyl)pyridin-3 -yl] ethyl I benzamide; Step A: methyl 3-bromo-5-iodobenzoate; To a suspension of 3-bromo-5-iodobenzoic acid (993 g, 3.04 mol) in methanol (6.0 L) was added hydrochloric acid (37%; 20.0 mL, 244 mmol). The mixture was heated to 70 0C. After 72 h, the mixture was cooled to ambient temperature. Dichloromethane (2.5 L) was added and the mixture was partially concentrated. The suspension was filtered and the filtered cake was washed with cold methanol to give the title compound as a white solid (846 g)-
The chemical industry reduces the impact on the environment during synthesis 3-Bromo-5-iodobenzoic acid. I believe this compound will play a more active role in future production and life.
Reference:
Patent; MERCK & CO., INC.; WO2009/58298; (2009); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com