Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2043-57-4, name is 1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 2043-57-4
15 mL of freshly distilled and dry THF under nitrogen was cooled to -78 C. 4.0 mL of LDA in THF (1 .0 M) (4 mmol) was added quickly. 0.332 mg [1 .8 mmol] of 4,4′-dimethyl-2,2′-bipyridine, dissolved in 3 ml of dry THF, were added and kept under stirring for 30 minutes at – 78 C, then for 15 minutes at -10 C and finally the temperature was cooled again at -78 C for further 15 minutes. Then 1 .896 g [4 mmol] of 1 H,1 H,2H,2H-perfluorooctyl iodide were added. After the addition, the reaction mixture was allowed to warm slowly to room temperature. The reaction was added with 20 ml of brine and extracted with diethyl ether and dried over Na2SO4. Evaporation u.v. (30 C/2.4 kPa) gave a crude product, that was purified by silica gel column chromatography eluting with methanol/dichloromethane solvent mixture, using an appropriate gradient (2:98 final eluting solvent mixture ratio). After removal of the solvent u.v. (30 C/ 2.4 kPa) 0.512 g of the desired compound was obtained as a white solid. 1H-NMR (400 MHz, CDCI3): 8.60 (d, 2H, J=5.1 Hz), 8.28 (s, 2H), 7.16 (dd, 2H, J=1 .6 Hz, J=3.3 Hz), 2.82 (t, 4H, J=7.5 Hz), 2.21 -1 .99 (m, 8H) ppm. 19F-NMR (376.3 MHz, CDCI3): -126.1 , -123.4, -122.8, -121 .9, -1 14.1 , -80.81 ppm.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 2043-57-4.
Reference:
Patent; TOZZI GREEN S.P.A.; BORZATTA, Valerio; ZAMA, Isabella; RIGHI, Paolo; GORNI, Giacomo; (39 pag.)WO2019/29789; (2019); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com