Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 20555-91-3, name is 1,2-Dichloro-4-iodobenzene, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 1,2-Dichloro-4-iodobenzene
A 3M solution of n-BuLi in hexane (24 mL) was added to anhydrous THF (60 mL) at -78 C., followed by the addition of a solution of compound X-A-49 (15 g) in anhydrous THF (10 mL) dropwise. The mixture was stirred for an hour, then compound X-B-49 was added dropwise. The resulting mixture was stirred at -78 C. for an additional hour then allowed to warm up gradually to room temperature. After stirring at room temperature for 3 hours, the reaction was quenched by adding a saturated aqueous NH4Cl solution dropwise. The separated organic layer was set aside. The aqueous was concentrated to remove most of the THF, then extracted with EtOAc (3×30 mL). The combined organic solution was dried over Na2SO4 and concentrated. The residue was purified by column chromatography eluting with petroleum ether/EtOAc (5:1) to give 9.5 g of compound X-C-49 in 54% yield.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 20555-91-3.
Reference:
Patent; Kalypsys, Inc.; US2005/234046; (2005); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com