Adding a certain compound to certain chemical reactions, such as: 6828-35-9, name is 5-Chloro-2-iodoaniline, belongs to iodides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6828-35-9, SDS of cas: 6828-35-9
General procedure: Aryl iodide or bromides (5.0 mmol),paraformaldehyde (5.0 mmol), Pd(OAc)2 (0.0005 mmol) (for aryliodides) or Pd(PPh3)4 (0.05 mmol) (for aryl bromides) andCs2CO3 (7.0 mmol) were reacted in DMSO at 80 oCfor 12 h. The reaction mixture was poured into H2O, and extractedwith Et2O. The internal standard (dodecane) was added to theresulting mixture, and the conversion of aryl iodide and the yield of thehydrodehalogenated product were calculated.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Chloro-2-iodoaniline, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Pyo, Ayoung; Kim, Sudeok; Kumar, Manian Rajesh; Byeun, Aleum; Eom, Min Sik; Han, Min Su; Lee, Sunwoo; Tetrahedron Letters; vol. 54; 38; (2013); p. 5207 – 5210;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com