Reference of 51560-21-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 51560-21-5, name is 1,4-Diiodo-2,5-dimethoxybenzene belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
General procedure: To a 10 mL headspace crimp vial equipped with a magnetic stirrer the corresponding styrene (2.0 mmol), aryl 1,4-dihalide precursor (1.0 mmol), bis(dibenzilidene)acetone palladium (0) (2.0 mol%) and triphenylphosphite (9.0 mol%) were added. The vial was then sealed with a PTFE septum and an aluminum cap followed by purge-saturation with argon. Dry DMF (3 mL) and triethylamine (2.0 mmol) were subsequently added via syringe. The reaction mixture was stirred at 110C for 24 hours. After reaction is complete, the crude was filtered over celite and precipitation of the product was induced by addition of cold water (75 mL). Recrystallization from a 2:1 DMF:1,4-dioxane afforded the desired OPVs.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,4-Diiodo-2,5-dimethoxybenzene, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Acelas, Mauricio; Sierra, Andres Felipe; Sierra, Cesar A.; Synthetic Communications; (2020);,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com