696-41-3, Adding some certain compound to certain chemical reactions, such as: 696-41-3, name is 3-Iodobenzaldehyde, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 696-41-3.
General procedure: A mixture of an aldehyde (1) (1.0 equiv), 2-aminobenzophenone (2) (1.0equiv), NH4OAc (3) (2.0 equiv), and DMAP (0.2 equiv.) in absolute EtOH (5 ml)was stirred at 40 C for the stipulated period of time (see Tables 2 and 3). Aftercompletion of the reaction, as monitored by TLC, the mixture was poured intoice-cold H2O and the solid product was filtered, washed with H2O (3-5 mL) anddried. The crude product was recrystallized from EtOAc to give puredihydroquinazolines. For compounds 4c, 4g, 4m, and 4p, after cooling, H2Owas added and the product was extracted with EtOAc (3 15 mL). Thecombined organic extract was washed with H2O, dried (anhyd Na2SO4) and thesolvent removed followed by flash column chromatography over silica gel (60-120 mesh) to furnish the desired product.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 696-41-3.
Reference:
Article; Derabli, Chamseddine; Boulcina, Raouf; Kirsch, Gilbert; Carboni, Bertrand; Debache, Abdelmadjid; Tetrahedron Letters; vol. 55; 1; (2014); p. 200 – 204;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com