88-67-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 88-67-5, name is 2-Iodobenzoic acid belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Add compound 5 (8.44 g, 34.03 mmol) to a 250 ml round bottom flaskAnd 60ml concentrated sulfuric acid, stir to 60 C and add N-bromosuccinimide(4.82 g, 38.06 mmol), reacted for 2 h, and after cooling to room temperature, the solution was dropped into ice water.Extracted with ethyl acetate, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure.Column chromatography gave 9.54 g of white solidCompound 6, yield 86%.
The synthetic route of 2-Iodobenzoic acid has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Dalian University of Technology; Wang Shisheng; Li Guangzhe; Liu Liqiang; Zhao Weijie; Guo Xiuhan; Li Yueqing; Wang Xu; Dong Huijuan; (21 pag.)CN110041200; (2019); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com