In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 31599-61-8 as follows. SDS of cas: 31599-61-8
General procedure: To the catalyst (1.0mol%) dissolved in 10ml THF in a 25ml round-bottom flask, aryl halide (1.0mmol), phenyl boronic acid (1.2mmol) and K2CO3 (2.0mmol) were all added. The mixture was stirred at refluxing temperature for 4h. After completion of the reaction, the mixture was evaporated to dryness, water was added and the product was extracted with dichloromethane. The organic layer was washed with brine, dried over Na2SO4, filtered, passed through a silica column (60-120 mesh), where the complex remained trapped. Upon removal of the solvent, pure solid products were obtained. The yields of the products obtained (based on the aryl halides) from all the reactions were determined after isolation, and the products were characterized by 1H NMR spectra and melting points by a comparison with the literature data.
According to the analysis of related databases, 31599-61-8, the application of this compound in the production field has become more and more popular.
Reference:
Article; Pratihar, Jahar Lal; Mandal, Paritosh; Lin, Chia-Her; Lai; Mal, Dasarath; Polyhedron; vol. 135; (2017); p. 224 – 230;,
Iodide – Wikipedia,
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