Continuously updated synthesis method about 624-76-0

According to the analysis of related databases, 624-76-0, the application of this compound in the production field has become more and more popular.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 624-76-0, name is 2-Iodoethanol, This compound has unique chemical properties. The synthetic route is as follows., category: iodides-buliding-blocks

1.47 g (3 mmol) of compound (4b) and 1.24 g (9 mmol) of potassium carbonate were added to a 50 ml round-bottomed flask. 25 ml of double distilled DMF was added and 0.7 ml (9 mmol) of iodoethanol was slowly added dropwise and the mixture was stirred at 50 C. for 8-12 h .After the reaction was completed, the reaction mixture was diluted with 100 ml of ethyl acetate and washed with water (25 ml × 4) to remove DMF. The organic phase was dried over anhydrous Na 2 SO 4 for 1 h,The filtrate was spin-dried over the column to give a pale yellow colored solid (5b) 1.08g, 67% yield.

According to the analysis of related databases, 624-76-0, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Yantai University; Wang Hongbo; Hong Xuechuan; Fu Fenghua; Tian Jingwei; Lv Zhenbin; Lei Lei; Ma Jinbo; Zhai Rong; Lv Guangyao; (11 pag.)CN106317050; (2017); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com