29632-73-3, name is 2-Bromo-4-iodoaniline, belongs to iodides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. COA of Formula: C6H5BrIN
2-bromo-4-iodoaniline (500 mg, 1.68 mmol) was added to an eggplant-shaped flask, and 10 mL of dry N,N-dimethylformamide was added. Sodium hydride (110 mg, 2.52 mmol) was added, and 1-bromo-2-methoxyethane (350 mg, 2.52 mmol). Heat to 100 C and stir overnight. After completion of the reaction, asaturated sodium chloride solution was added, it was extracted with ethyl acetate three times, and the organic phases were combined, dried over anhydrous sodiumPurified on a silica gel column to obtain the target compound 576 mg.
The synthetic route of 29632-73-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Chinese Academy Of Sciences Shanghai Pharmaceutical Institute; Zhao Yujun; Li Zhiqiang; Yan Ziqin; Li Jia; Zhou Yubo; Su Mingbo; Chen Zheng; (138 pag.)CN109810110; (2019); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com