Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 624-76-0, name is 2-Iodoethanol, This compound has unique chemical properties. The synthetic route is as follows., Formula: C2H5IO
Add to the reaction bottleThioacetic acid (874 mg, 11.5 mmol),2-iodoethanol (1.72 g, 10 mmol),Dissolved in 15 ml of anhydrous toluene,1,8-diazabicycloundec-7-ene (DBU, 1.75 g, 11.5 mmol) was added dropwise at 0 C.5 ml of toluene solution, plus,The reaction was stirred for 2 hours at room temperature.After TLC detects the reaction,Dilute with a small amount of water,Divide the organic phase,Washed with saturated brine and concentrated.Purified by column chromatography,The product was dried under vacuum to give 576 mg,yield: 48%.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 624-76-0.
Reference:
Patent; Shenzhen Tajirui Bio-pharmaceutical Co., Ltd.; Wang Yihan; Zhao Jiuyang; (46 pag.)CN109485676; (2019); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com