Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 612-55-5, name is 2-Iodonaphthalene, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 2-Iodonaphthalene
Bis(t?phenylphosphine)palladium (II) chloride (0 18 g, 0 26 mmol, 0 18 mol %) was added to a stirred solution of propargyl alcohol (8 43 mL, 144 8 mmol, 1 eq ), 2-iodonapthalene (36 g, 142 mmol), t?ethylamine (39 6 mL, 284 mmol, 2 eq ) and copper iodide (0 09 g, 0 49 mmol, 0 3 mol %) in tetrahydrofuran (750 ml) The mixture was stirred at 35 0C for 12 h under nitrogen atmosphere The mixture was then filtered through a bed of cehte and the filtrate was washed with ethyl acetate (200 ml) The filtrate was then concentrated in vacuo Purification by silica gel chromatography using 1 6 ethyl acetate/petrol as the eluting solvent afforded the desired compound (2 85 g, 1 1%) as a white solid 1H NMR (400 MHz, CDCl3) delta ppm 4 54 (2H, s, CH2), 7 45-7 49 (3eta, m, ArH), 7 75-7 81 (3eta, m, ArH), 7 95 (1eta, s, ArH)
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 612-55-5.
Reference:
Patent; DOV PHARMACEUTICAL, INC.; WO2008/57575; (2008); A2;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com