Synthetic Route of 328-73-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 328-73-4, name is 1-Iodo-3,5-bis(trifluoromethyl)benzene belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
The ligand L2 prepared in Example 4 was used as a reactant, 3,5-bistrifluoromethyliodobenzene, cuprous iodide, N,N’-dimethyl-1,2-ring in a xylene solvent. The hexamethylenediamine and potassium phosphate were reacted at a molar ratio of 1:2.0:0.2:0.4:2.0 at 90 °C for 6 hours, cooled to room temperature, diluted with ethyl acetate, filtered, concentrated, and obtained by column chromatography. The solid, ie the ligand shown by L4 (77percent yield), the specific synthetic route is as follows:
The synthetic route of 1-Iodo-3,5-bis(trifluoromethyl)benzene has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Shang Gu Science And Technology (Tianjin) Co., Ltd.; Wang Xiaomin; (35 pag.)CN108774216; (2018); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com