Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 6940-76-7, name is 1-Chloro-3-iodopropane, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of 1-Chloro-3-iodopropane
EXAMPLE 2; 4-Hydroxy-4-methyl-cyclohexanecarboxylic acid (3-chloro-4-methyl-phenyl)-{3-[5-(4,6-dimethyl-pyrimidine-5-carbonyl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-propyl}-amide, trifluoroacetate salt (I-16); Step 1-; A mixture of aniline (1 mL, 11.1 mmol), 1-chloro-3-iodo-propane (1.31 mL, 12.2 mmol) and Cs2CO3 (10.8 g, 33.3 mmol) in DMF (15 mL) was stirred at RT overnight. It was diluted with water and extracted with hexane. The organic layer was dried (Na2SO4), filtered and evaporated in vacuo. The residue was purified via SiO2 chromatography eluting with hexane/EtOAc, (95/5) to afford 2.52 g (67%) of 19a (Ar=Ph) as an oil: M+H=170.
According to the analysis of related databases, 6940-76-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Roche Palo Alto LLC; US2007/191406; (2007); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com