Related Products of 52914-23-5, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 52914-23-5, name is 2-(4-Iodophenyl)ethanol, This compound has unique chemical properties. The synthetic route is as follows.
Into a 50-mL 3-necked round-bottom flask under N2 was placed a solution of 2- (4-iodophenyl)ethanol (470 mg, 1.90 mmol) in tetrahydrofuran (10 mL). Sodium hydride (91 mg, 3.8 mmol, 1.2 equiv.) was added at 0 0C. The mixture was warmed to room temperature and stirred at room temperature for 2 h. Benzyl bromide (272 muL, 3.9 mmol, 1.2 equiv.) and tetra-w-butylammonium bromide (61 mg, 0.19 mmol, 0.10 equiv.) were added at room temperature. The resulting solution was stirred for 20 h at room temperature. The reaction was then quenched by the addition of 10 mL of aqueous NH4CI. The solution was extracted with 3 x 60 mL of EtOAc, and the organic layers were combined and washed with 50 mL of brine. After evaporation, the residue was applied onto a silica gel column, and the product was eluted with EtO Ac/petroleum ether 1:20 to furnish 600 mg (94%) of l-[2- (benzyloxy)ethyl]-4-iodobenzene as a white solid.
The chemical industry reduces the impact on the environment during synthesis 2-(4-Iodophenyl)ethanol. I believe this compound will play a more active role in future production and life.