Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 628-77-3, name is 1,5-Diiodopentane, A new synthetic method of this compound is introduced below., COA of Formula: C5H10I2
Step 1: preparation of tert-butyl (trans-4-(piperidin-1-yl)cyclohexyl)carbamate Tert-butyl (trans-4-aminocyclohexyl)carbamate (214 mg, 1 mmol) and 1,5-diiodopentane (324 mg, 1 mmol) were dissolved in acetonitrile (5 mL). The reaction liquid was added with potassium carbonate (414 mg, 3 mmol), and reacted at 70 C for 2 hours. The reaction liquid was concentrated to dryness, dissolved in ethyl acetate (10 mL), washed with saturated brine, and the organic phase was dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 250 mg of a pale yellow solid. Yield: 88.6%. MS (ESI, m/z): [M+H]+: 283.3.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.