Application of 31970-26-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 31970-26-0, name is 1-(4-Iodophenyl)propan-1-one belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Finely powdered cuprous bromide (20.21 g, 91 mmol) was suspended in ethyl acetate (30 mL) and heated to reflux. A solution of ketone (14 g, 54 mmol) in chloroform (30 mL) was added dropwise over 10 minutes. After refluxing for 7 hours, the reaction was left to cool overnight and filtered through Celite. The filtrate was washed with saturated aqueous sodium bicarbonate (2¡Á50 mL) and brine (50 mL), dried over magnesium sulfate and concentrated under reduced pressure. Recrystallization from hexane afforded a pale yellow solid. mp 76 C. Yield 12.2 g (66%). 1H NMR (CDCl3) delta7.83 (d, 2H), 7.72 (d, 2H), 5.21 (q, 2H), 1.87 (d, 3H). MI=338. IR (Liq film) cm-1 1677. Calculated for C9H8BrIO: C, 31.9%, H, 2.38%. Found: C, 32.2%, H, 2.5%.
The synthetic route of 1-(4-Iodophenyl)propan-1-one has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Tisdell, Francis Eugene; Bis, Scott Jerome; Hedge, Vidyadhar Babu; Martin, Timothy Patrick; Perreault, Denise Marie; Yap, Maurice Chee Hoong; Guenthenspberger, Katherine Anne; Dripps, James Edwin; Gifford, James Michael; Schoonover, Joe Raymond; Karr, Laura Lee; Dintenfass, Leonard Paul; Neese, Paul Allen; US2004/6108; (2004); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com