Related Products of 19099-54-8, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 19099-54-8, name is 1-Iodo-2-isopropylbenzene belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
A mixture of N,7-[(benzothiazol-2-yl)-9,9-diethylfluoren-2-yl)-N-(2,6-diisopropylphenyl)amine (Example 19; 4.24 g, 8 mmol), 2-isopropyl iodobenzene (12.3 g, 50 mmol), 18-crown-6 (0.169 g), copper powder (1 g, 15.7 mmol) and potassium carbonate (4.41 g, 32 mmol) was kept at 240 C. for 4 hours under nitrogen, cooled, diluted with toluene and filtered. The filtrate was washed with water, dried and concentrated. The residue (15.32 g) was chromatographed over silica gel. The column was eluted with 1:1 toluene to get the product, and the product was crystallized from a mixture of isopropanol and toluene, 3.85 g (74%), m.p. 259.3-262.9 C. Mass spec: m/z 648 (M+). Anal. Calcd. for C45H48N2S: C, 83.29; H, 7.46; N, 4.32 and S, 4.94%. Found: C, 83.33; H, 7.45; N, 4.31 and S, 4.96%. 1H NMR (CDCl3) delta ppm: 0.29, 0.32 (2t, 6H, 7.28, 7.36 Hz), 0.75 (broad envelope 6H), 1.18 (broad, 12H), 1.90 (m, 2H), 2.08 (m, 2H), 3.20 (broad s?, 2H), 3.35 (m, 1H), 6.58 (m, 1H), 6.81 (dd, 1H, 1.32 and 7.88 Hz), 7.08 (m, 2H), 7.23 (m, 3H), 7.34 (m, 3H), 7.47 (m, 2H), 7.62 (d, 1H, 7.92 Hz), 7.88 (d, 1H, 7.88 Hz), 7.99 (m, 2H). 13C NMR delta ppm: 8.33, 8.60, 21.46, 23.85, 27.66, 28.00, 28.57, 32.50, 32.90, 56.55 (10 sp3C), 118.89, 119.76, 120.75, 121.30, 121.49, 122.87, 124.27, 124.85, 125.30, 125.78, 126.22, 126.43, 127.18, 127.87, 128.23, 129.04, 130.86, 132.95, 134.91, 142.58, 142.88, 143.53, 145.02, 148.05, 148.19, 150.06, 151.86, 152.06, 154.29 and 169.02 (30 sp2C).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Iodo-2-isopropylbenzene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; The United States of America, as represented by the Secretary of the Air Force; Tan, Loon-Seng; Kannan, Ramamurthi; (43 pag.)US10113065; (2018); B1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com