628-21-7, A common heterocyclic compound, 628-21-7, name is 1,4-Diiodobutane, molecular formula is C4H8I2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
In a 250 mL three-necked flask was added 19.4 g of anthrone (0.1 mol), 150 mL of dry THF, under stirring, 34. 1 g of 1,4-diiodobutane (0.1 1 mol) and 26.8 g of potassium tert-butoxide (0.24 mol) the reaction was stirred at room temperature for 3 h and refluxed for 3 h. The reaction was quenched by the addition of saturated ammonium chloride solution, extracted with ethyl acetate, separated by column chromatography, and 13.6 g of white solid B-I was obtained by column chromatography. The yield was 55%
The synthetic route of 628-21-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Kunshan Weixinnuo Display Co., Ltd.; Tsinghua University; Beijing Weixinnuo Technology Co., Ltd.; Qiu Yong; Fan Hongtao; (61 pag.)CN103508940; (2017); B;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com