1878-94-0, name is 2-(4-Iodophenoxy)acetic acid, belongs to iodides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. 1878-94-0
Step 3: N-(3-Fluoro-4-methanesulfonylamino-benzyl)-2-(4-iodo- phenoxy)-acetamide; 3-Fluoro-4-methanesulfonylamino-benzylamine HCI salt (120 mg, 0.471 mmol), NMP (0.25 ml), and (4-iodo-phenoxy)-acetic acid (121 mg, 0.435 mmol) were added in THF (50 ml). After the mixture was stirred for 10 min, DMTMM (138 mg, 0.500 mmol) was added into the mixture. The reaction mixture was stirred overnight. The reaction solvent was removed in vacuo. The resulting residue was extracted with ethyl acetate (60 ml) and H2O (30 ml). The organic layer was washed with saturated K2CO3 (30 ml), 5% HCI solution (30 ml) and brine (30 ml). The organic layer was dried with MgSO4 and concentrated in
Statistics shows that 1878-94-0 is playing an increasingly important role. we look forward to future research findings about 2-(4-Iodophenoxy)acetic acid.
Reference:
Patent; AMOREPACIFIC CORPORATION; WO2007/120012; (2007); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com