Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 41252-96-4, name is 2-Chloro-1-iodo-4-nitrobenzene, This compound has unique chemical properties. The synthetic route is as follows., name: 2-Chloro-1-iodo-4-nitrobenzene
General procedure: 4-acryloyloxy-2,2,6,6-tetramethylpiperidin-1-oxyl (3, 0.113 g,0.5 mmol), aryl iodide (4a-i, 0.5 mmol), Bu4N+AcO- (hygroscopic)(0.3 g), PdEnCatTOTP30 (0.0625 g, 0.025 mol,5 mol %), and toluene (2 mL) were placed in a flask, stirred and heated at 80-100 C for 20-27 h under argon. The particular temperatures and times of the reactions are summarized in Table 1. After approximately 6 h, a second portion of a catalyst(0.0625 g, 0.025 mol, 5 mol %) was added. The progress of the reaction was monitored by TLC (silica, hexane/ethyl acetate9:1). Upon completion of the reaction, the solids were filtered off, the dark filtrate was concentrated under reduced pressureand subjected to column chromatography (hexane/ethyl acetate 9:1, benzene/ethyl acetate 95:5, benzene/methanol 95:5 aspossible mobile phases). The red zone was collected, the eluate was evaporated under reduced pressure to yield red oils (solidifiedin a refrigerator), or directly red crystals of 5a-i.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 41252-96-4.
Reference:
Article; Zakrzewski, Jerzy; Huras, Bogumila; Beilstein Journal of Organic Chemistry; vol. 11; (2015); p. 1155 – 1162;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com