Reference of 5326-39-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 5326-39-6, name is 1-Iodo-4-methyl-2-nitrobenzene belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
A mixture of i-1 (1-Iodo-4-methyl-2-nitro-benzene, 0. 0038 mol), methyl-vinylketone (0.0076 mol), Et3N (0.0076 mol) and Pd (OAc) 2 (0.00019 mol) in CH3CN (6 ml) were stirred in a microwave oven (100C, 100 W) for 5 min. The reaction was then filtered through a pad of celite and the filtrate was concentrated. The residue was purified by column chromatography over silica gel (eluent: CH2Cla/Cyclohexane 70/30). Yield: 0.65 g of i-2 (4- (4-Methyl-2-nitro-phenyl)-but-3-en-2-one, 78%, melting point: 58C).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Iodo-4-methyl-2-nitrobenzene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; TIBOTEC PHARMACEUTICALS LTD.; WO2005/58871; (2005); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com