Related Products of 19230-28-5, These common heterocyclic compound, 19230-28-5, name is 1,3-Dichloro-2-iodobenzene, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: To a stirred solution of complex 1 (10 mg, 0.0125 mmol) in a mixed solvent of n-heptane (1.5 mL) and water (1.5 mL) were added KCN (10.6 mg, 0.1625 mmol), ZnCl2 (11.1 mg, 0.0825 mmol), NaBH4 (0.5 mg, 0.0125 mmol), and iodobenzene (26 mg, 0.125 mmol). The reaction mixture was stirred at 100 C for 1 h under nitrogen atmosphere. After cooling the reaction mixture in an ice-bath, aliquots of the organic layer were transferred to a vial with a Pasteur pipette. Eluting the aliquots with diethyl ether on a short glass-column (0.7 ¡Á 15 cm) packed with alumina (ca. 1 cm) resulted in a clear yellowish solution which was analyzed with GC/MS.
Statistics shows that 1,3-Dichloro-2-iodobenzene is playing an increasingly important role. we look forward to future research findings about 19230-28-5.
Reference:
Article; Shim, Young Ji; Lee, Ho Jin; Park, Soonheum; Journal of Organometallic Chemistry; vol. 696; 26; (2012); p. 4173 – 4178;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com