Alkoxyboration: Ring-Closing Addition of B-O 锜?Bonds across Alkynes was written by Hirner, Joshua J.;Faizi, Darius J.;Blum, Suzanne A.. And the article was included in Journal of the American Chemical Society in 2014.SDS of cas: 207115-22-8 This article mentions the following:
For nearly 70 years, the addition of boron-X 锜?bonds to carbon-carbon multiple bonds has been employed in the preparation of organoboron reagents. However, the significantly higher strength of boron-oxygen bonds has thus far precluded their activation for addition, preventing a direct route to access a potentially valuable class of oxygen-containing organoboron reagents for divergent synthesis. Authors herein report the realization of an alkoxyboration reaction, the addition of boron-oxygen 锜?bonds to alkynes. Functionalized O-heterocyclic boronic acid derivatives are produced using this transformation, which is mild and exhibits broad functional group compatibility. The results demonstrate activation of this boron-O 锜?bond using a gold catalysis strategy that is fundamentally different from that used previously for other boron addition reactions. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8SDS of cas: 207115-22-8).
4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Iodide-containing intermediates are common in organic synthesis, because of the easy formation and cleavage of the C閳ユ彂 bond. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.SDS of cas: 207115-22-8
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com