Catalyst as colour indicator for endpoint detection to enable selective alkyne trans-hydrogenation with ethanol was written by Wang, Yulei;Huang, Zhidao;Huang, Zheng. And the article was included in Nature Catalysis in 2019.Safety of N,N-Diethyl-4-iodobenzamide This article mentions the following:
An iridium complex catalyzed semi-hydrogenation of internal alkynes using ethanol as hydrogen donor to afford E-alkenes and Et acetate was reported. Importantly, issues of over-reduction and stereoselection was successfully addressed by using a color change effect due to shift of catalyst resting states, thereby precisely detecting the endpoint of the reaction. This catalytic system was applicable to a wide variety of internal alkynes bearing many auxiliary functional groups, and its utility for synthesis of biol. relevant mols. was also demonstrated. In the experiment, the researchers used many compounds, for example, N,N-Diethyl-4-iodobenzamide (cas: 77350-52-8Safety of N,N-Diethyl-4-iodobenzamide).
N,N-Diethyl-4-iodobenzamide (cas: 77350-52-8) belongs to iodide derivatives. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons鑱砈mith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Safety of N,N-Diethyl-4-iodobenzamide
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com