A new, improved and convenient synthesis of 4H-cyclopenta[2,1-b:3,4-b’]-dithiophen-4-one was written by Brzezinski, Jacek Z.;Reynolds, John R.. And the article was included in Synthesis in 2002.Reference of 474416-61-0 This article mentions the following:
A new and efficient three-step synthesis of 4H-cyclopenta[2,1-b:3,4-b’]dithiophen-4-one is described. This was achieved by a one-pot, regiospecific synthesis of bis(2-iodo-3-thienyl)methanol, its subsequent oxidation to the bis(2-iodo-3-thienyl) ketone which after Ullmann coupling yielded the title compound In the experiment, the researchers used many compounds, for example, Bis(2-iodothiophen-3-yl)methanone (cas: 474416-61-0Reference of 474416-61-0).
Bis(2-iodothiophen-3-yl)methanone (cas: 474416-61-0) belongs to iodide derivatives. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons鑱砈mith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Reference of 474416-61-0
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com