Zeolites Catalyze the Nazarov Reaction and the tert-Butylation of Alcohols by Stabilization of Carboxonium Intermediates was written by Tejeda-Serrano, Maria;Sanz-Navarro, Sergio;Blake, Finn;Leyva-Perez, Antonio. And the article was included in Synthesis in 2020.SDS of cas: 877264-43-2 This article mentions the following:
Here, it shows that representative carboxonium-mediated organic reactions, such as Nazarov cyclization and tert-butylation of alcs. C6H5CCC(OH)(R1)R2 (R1 = Ph, R2 = H; R1 = R2 = Ph; R1 = R2 = H) with tert-Bu acetate, typically performed with very strong acid catalysts in solution such as triflic acid, can be catalyzed by simple zeolites with high yield and selectivity. The aluminosilicate framework stabilizes the intermediate carboxonium species and overrides the need for superacid protons in solution Zeolites are the most used catalysts worldwide in petrochem. processes, with particular ability to stabilize carbocations. However, the use of zeolites in organic synthesis is still scarce. In the experiment, the researchers used many compounds, for example, (5-Fluoro-2-iodophenyl)methanol (cas: 877264-43-2SDS of cas: 877264-43-2).
(5-Fluoro-2-iodophenyl)methanol (cas: 877264-43-2) belongs to iodide derivatives. Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I.SDS of cas: 877264-43-2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com