Total synthesis of (±)-13-epineostenine was written by Tang, Meng;Fan, Chun-An;Zhang, Fu-Min;Tu, Yong-Qiang. And the article was included in Tetrahedron in 2009.Formula: C4H8ClI This article mentions the following:
An efficient total synthesis of (±)-13-epineostenine (I) has been achieved in 15 steps and 17% overall yield. This approach involved the key alkylation/Michael additions of the central 1,4-cyclohexanedione monoethylene acetal and all of the stereocenters on central cyclohexane moiety were generated in highly stereoselectivity. In the experiment, the researchers used many compounds, for example, 1-Chloro-4-iodobutane (cas: 10297-05-9Formula: C4H8ClI).
1-Chloro-4-iodobutane (cas: 10297-05-9) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Polyiodoorganic compounds are sometimes employed as X-ray contrast agents, in fluoroscopy, a type of medical imaging. This application exploits the X-ray absorbing ability of the heavy iodine nucleus.Formula: C4H8ClI
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com