4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I.Electric Literature of C8H9IO2
Iridium-Catalyzed Asymmetric Hydrogenation of 2,3-Diarylallyl Amines with a Threonine-Derived P-Stereogenic Ligand for the Synthesis of Tetrahydroquinolines and Tetrahydroisoquinolines was written by Rojo, Pep;Molinari, Medea;Cabre, Albert;Garcia-Mateos, Clara;Riera, Antoni;Verdaguer, Xavier. And the article was included in Angewandte Chemie, International Edition in 2022.Electric Literature of C8H9IO2 This article mentions the following:
The synthesis of a family of P-stereogenic phosphinooxazoline iridium catalysts from L-threonine Me ester and their use in the asym. hydrogenation of N-Boc-2,3-diarylallyl amines, achieving very high enantioselectivity was reported. Furthermore, the synthetic utility of the 2,3-diarylpropyl amines obtained was demonstrated by their transformation to 3-aryl-tetrahydroquinolines and 4-benzyl-tetrahydroisoquinolines, which had not yet been obtained in an enantioselective manner by direct reduction of the corresponding aromatic heterocycles. This strategy allowed the preparation of these types of alkaloids with the highest enantioselectivity reported up to date. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2Electric Literature of C8H9IO2).
4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I.Electric Literature of C8H9IO2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com